June 18, 2019
IRAK4 degraders for MYD88 mutant lymphoma
International Conference on Malignant Lymphoma (ICML)
MYD88 Tumors
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March 29, 2019
KYM-001, first-in-class oral IRAK4 protein degraders, induce tumor regression in a xenograft model of MYD-88 mutant ABC DLBCL alone and in combination with BTK inhibition
American Association for Cancer Research (AACR) Annual Meeting
MYD88 Tumors
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January 28, 2019
Targeted Protein Degradation Mechanisms
Zhang, Y., Loh, C., Chen, J., & Mainolfi, N. (2019). Targeted protein degradation mechanisms. Drug Discovery Today: Technologies, 31, 53-60.
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December 1, 2018
Targeted degradation of IRAK4 protein via heterobifunctional small molecules for treatment of MYD88 mutant lymphoma
American Society of Hematology (ASH) Annual Meeting
MYD88 Tumors
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October 9, 2017
Targeted Protein Degradation (chapter 9), Annual reports in medicine chemistry
Mainolfi, N., & Rasmusson, T. (2017). Targeted protein degradation. In R. A. Goodnow (Ed.), Annual reports in medicinal chemistry (Vol. 50, pp. 301-334). Academic Press.
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